PolyX karyotypes are associated with numerous phenotypes, biology sex linked genes in Wiltshire mental retardation and growth effects Rooman et al. Therefore, if recessivity is the biology sex linked genes in Wiltshire cause of faster X, the elevated adaptive substitution rate on the X chromosome should be seen mostly in genes expressed early in spermatogenesis.
Advanced Search. The male-based and female-based test statistics are weighted by the square-root of the male or female sample size  and combined while also taking into account the direction of effect in males and females.
As with our above analyses, we combined SNP-level results to a gene-based test of sex-differentiated effect size. Indeed, we found a strong negative correlation in expression levels between reciprocal hybrids in round spermatids, while there was a weak non-significant positive trend coincident with the disruption of MSCI in diplotene spermatocytes supplementary fig.
Signals of genomic conflict in sex-linked gene expression in round spermatids. Imagine we focus on an X-linked gene. A useful way to make progress is to compare patterns of adaptive evolution among different categories of loci.
Meiotic sex chromosome inactivation is disrupted in sterile hybrid male mice. However, it has remained unclear how these phenomena impact the global landscape of sex-linked and autosomal gene expression in sterile males Good et al.
In situ hybridization of male and female brain sections from the cerebellum, DLPFC, and anterior cingulate cortex.
The predominance of hybrid male sterility in XY systems Laurie ; Presgraves ; Delph and Demuth indicates that having distinct sex chromosomes renders spermatogenesis unusually prone to hybrid breakdown. It could be the case that there is one X-linked gene that within the cell culture has mutated and is polymorphic for a previously identified SNP although this is unlikely to explain repeated heterozygosity.
Figure S4: Simulation versus permutation derived p-values for gene-set tests for FM If instead selection targets standing variation, autosomal loci can evolve faster than X-linked loci Charlesworth et al.